Andarine, also known as S-4, S-40503, or 8, is a SARM developed with the aim of treating osteoporosis and muscle wasting.
SARMs (selective androgen receptor modulators) are drugs that bind to the androgen receptor (AR), which is the main site of action of the hormone testosterone.
In the early days, Andarine was described as the ideal SARM due to high oral bioavailability and great muscle- and bone-building effects (studied in animals)
Phase I human trials with this drug have reportedly been successful but no studies have been published. However, further development of the drug was abandoned in favor of Ostarine, another SARM with a similar structure, also known as S-22.
We can presume that this was either because Ostarine was more effective, or because Andarine caused vision-related side effects (see below).
Andarine, commonly known as S4, is a Selective Androgen Receptor Modulator (SARM) developed by GTx. Like all SARM’s S4 was developed in the treatment of muscle wasting diseases with benign prostatic hypertrophy treatment also being high on the list of possible treatment benefits. Andarine is not as strong as some of the other SARM’s in terms of an anabolic effect that leads to the promotion of lean muscle tissue increases, but it does appear to have other benefits that can prove to be highly valuable. Being an effective SARM, like most SARM’s it is relatively side effect friendly with most users making it an increasingly common option for performance enhancing athletes.
Andarine (S4) Function and Traits
Anadarine (S4) is a SARM, specifically a medication that binds firmly to the androgen receptors. Unlike an anabolic androgenic steroid, S4 focuses only on the bone and muscle sites unlike other androgenic compounds that may affect secondary sex organs. By binding to the androgen receptors, S4 alters the gene expression, thereby increasing anabolism via increases in protein synthesis. Although a highly effective compound, in comparison to its binding affinity it is approximately one third that of testosterone.
Andarine (S4), unlike many androgens, does not convert to dihydrotestosterone (DHT) and it does not aromatize. Aromatization refers to the conversion of testosterone to estrogen. This makes S4 a bit more appealing on a functional basis compared to other androgenic compounds as negative DHT and Estradiol effects cannot occur with this compound. In fact, S4 has been shown to block DHT from binding to the prostate receptor sites.
S4 is based off of the same template molecularly as the drug Bicalutamide, an anti-androgen. However, unlike Bicalutamide, the severe negative effects of that drug are not present with Andarine – while a similar template it is not the same drug.
1) May Increase Muscle Mass
This drug was developed to prevent muscle wasting, and animal studies do indeed show that Andarine improves muscle growth and strength in animals.
When given to castrated rats for 4 weeks, Andarine increased muscle weight as markedly as DHT (dihydrotestosterone). Moreover, unlike DHT, Andarine caused no prostate enlargement, which is a concern when taking steroids [4].
Twelve weeks after castration, Andarine was able to restore lean body (muscle) mass in rats [5].
2) May Increase Bone Strength and Combat Osteoporosis
Andarine increased bone mineral density and strength in both in castrated male rats and in female rats whose ovaries had been removed (this is a commonly used animal model of osteoporosis) [4, 5, 6, 7].
Andarine may be especially beneficial in osteoporosis because, in addition to improving bone density, it also improves muscle strength, which may help reduce the risk of falls and fractures [7].
3) May Help Fat Loss
In female rats whose ovaries have been removed, apart from improving bone strength, Andarine also decreased body fat [7].
Make an order |
Please make clear what product and what quantity you need |
Quote |
Prices and Specifications details would be offered for you to consider and confirm |
Payment ways |
Bank Transfer, Western Union, Money Gram and Bitcoin |
Delivery ways |
All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.) |
Shipping address |
Provide your Valid and Correct destination address info(if possible with post code, phone number). |
Packing |
Select best ways according to quantity and safety degree(Super discreet, professional and experienced) |
Lead time |
Within 8 hours upon receipt of payment |
Package picture |
Photos of package would be offered to tell apart the items |
Tracking number |
Offered once it is released |
Shipping time |
3-7 working days (Door-to-Door) |
After-sale service |
24/7 Online for any problems |
Hjtc (Xiamen) Industry Co., Ltd.
Xiamen Huayongjian Biotechnology Co., Ltd.
Contacts: June & Eason
Whatsapp:+8618206063252; +8618759200098
E-mail: june@steroidpowder-hjtc.com;
eason@steroidpowder-hjtc.com
Web site:https://www.steroidpowder-hjtc.com/
http://www.safeststeroid.com/
http://www.glassviallabels.com/
https://hjtc-printing.en.made-in-china.com/
1.For products exported we can offer COA Certificate and official PI.
2.We are manufacturer with own lab and factory, can provide high quality products with factory price.
3.Products can be sent out in 24 hours after payment. Tracking number available, fixed service person are 7x24h for you to contact.
4.Secure and discreet shipment. Various transportation methods for your choice, like DHL/UPS/TNT/FedEx/SF-express.
5.Customs pass and satisfied rate ≥99%.
6.For hot sale products we have stock in there for transferring.
7.Products purity is test by our quality department strictly before sending, and you can askthe third testing organization come and inspect, such as (SGS/ CTI/ ITS), only after our confirmation will we send it out to you.
8.We have different couriers to different countries.
9.We have clients throughout the world.
1. Any inquiries will be replied within 24 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
Products name | Specification | |
1. | MGF | 2mg / vial |
2. | PEG MGF | 2mg / vial |
3. | CJC-1295 with DAC | 2mg / vial |
4. | CJC-1295 without DAC | 2mg / vial |
5. | PT-141 | 10mg / vial |
6. | MT-1 | 10mg / vial |
7. | MT-2 | 10mg / vial |
8. | GHRP-2 | 5mg / vial |
9. | GHRP-2 | 10mg / vial |
10. | GHRP-6 | 5mg / vial |
11. | GHRP-6 | 10mg / vial |
12. | Ipamorelin | 2mg / vial |
13. | Hexarelin | 2mg / vial |
14. | Sermorelin | 2mg / vial |
15. | Oxytocin | 2mg / vial |
16. | TB500 | 2mg / vial |
17. | Pentadecapeptide BPC 157 | 2mg / vial |
18. | HGH 176-191 | 2mg / vial |
19. | Triptorelin | 2mg / vial |
20. | Tesamorelin | 2mg / vial |
21. | Gonadorelin | 2mg / vial |
22. | Gonadorelin | 10mg / vial |
23. | DSIP | 2mg / vial |
24. | Selank | 5mg / vial |
ID | Item | Capacity |
1 | MK677 | 10mg*100/bottle |
2 | LGD4033 | 10mg*100/bottle |
3 | SR9009 | 10mg*100/bottle |
4 | RAD140 | 10mg*100/bottle |
5 | MK2866 | 10mg*100/bottle |
6 | AICAR | 10mg*100/bottle |
7 | Andarine | 10mg*100/bottle |
8 | GW-501516 | 10mg*100/bottle |
9 | YK11 | 10mg*100/bottle |
Q1: Can I get some samples?
A: Sure, we offer free sample, you just need to pay the shipping cost.
Q2: How to make orders?
A: Please send inquiry to us, then we will do the offer. Payment via Western Union, Moneygram, Bank Account and Bitcoin. Then we will arrange shipping. After delivery we will offer tracking No..
Q3: Is the shipping 100% Guarantee?
A: Yes, we offer 100% Shipping Guarantee. If any seized parcel we will do resending.
Q4: How to delivery?
A: Parcel will be shipped out in 3 working days after payment. Usually we use EMS, ePacket, Fedex, DHL, TNT and USA Domestic mixed shipping and so on.
Q5: Is there any discount?
A:Yes. The price is negotiable. Just send us the items you need and the quantity. We will apply the best price and offer discount for you.
Q6: What is the Minimum order quantity?
A: Usually MOQ is 100g. But depends on the items and your requirements we also can do 10g, 20g, 30g or 50g.